Medicine College

if a patient with renal disease shows depleted vitamin d levels, which function of the kidneys is affected?

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Answer 1

The function of vitamin D activation in the kidneys is affected in patients with renal disease who show depleted vitamin D levels. Vitamin D is activated in the kidneys by an enzyme called 1-alpha-hydroxylase.

In patients with renal disease, the kidneys may not function properly, leading to decreased activation of vitamin D. This can result in depleted vitamin D levels and subsequent issues such as bone density loss, increased risk of fractures, and impaired immune function.

Therefore, the function of vitamin D activation in the kidneys is affected in these patients. The kidneys play a crucial role in converting inactive vitamin D to its active form, calcitriol. In patients with renal disease, the ability of the kidneys to perform this conversion is impaired, leading to depleted levels of active vitamin D.

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