olecular diagnostic techniques that can help diagnose hemoglobin disorders such as hemoglobinopathies and thalassemias include a) biochemical separation, identification, and quantification of mixture components b) separation of macromolecules and their fragments, based on their size and charge c) DNA amplification, hybridization, and nucleotide sequencing d) The use of specific monoclonal antibodies

Answers

Answer 1

Answer:

The correct answer is - a) biochemical separation, identification, and quantification of mixture components.

Explanation:

Most hemoglobin disorders can be diagnosed by molecular diagnostic techniques such as protein-based techniques like electrophoresis and chromatography. Protein-based methods can diagnose early thalassemia disorders and hemoglobinopathies but in the case of α-thalassemia may be masked in the presence of β-thalassemia.

Molecular genetic testing plays a very important role in the biochemical separation of molecules or components, identification, and quantification of individuals carrying thalassemia and hemoglobinopathies traits and other hemoglobin disorders.


Related Questions

Her eyes are wide-set and slightly slanted. Her nose is short and flat, and she keeps her mouth slightly open. There is a straight crease across her palm, and her fifth digit is unusually short. The doctor tells her parents she has an inherited disorder. If you were the doctor what would you diagnosis Kate with? Discuss the etiology of Kate’s disorder? What is the biggest risk factor for this disorder? How can or will this disorder affect Kate? What test could have been completed to diagnosis this disorder before Kate’s birth?

Answers

Answer:

- These morphological features belong to Down syndrome.

- Diagnosis: Down syndrome (Trisomy Extra chromosome 21).

- Etiology: the presence of three copies of the autosomal chromosome 21 instead of two copies in body (somatic) cells.

- Most important health problem: Down syndrome increases the risk of developing Alzheimer's disease (other health problems include heart congenital defects, vision problems, hearing loss, hypothyroidism)

- Diagnostic test: Amniocentesis

Explanation:

Down syndrome (DS) is the most frequent chromosomal abnormality which is generally caused by the presence of an extra copy of autosomal chromosome 21, thereby it is an autosomal trisomy (trisomy 21). DS is often associated with intellectual disability and increased risk of developing Alzheimer's, as well as health problems including, among others, heart congenital defects, vision problems, hypothyroidism, blood disorders, hypotonia, endocrine problems, dental problems, seizures, etc. Amniocentesis is the most common invasive prenatal diagnostic procedure which is used to identify chromosomal abnormalities such as trisomy 21 (Down syndrome). Amniocentesis is done between 15 weeks and 20 weeks of pregnancy.

If the contents of a cell have a solute concentration of 0.04 percent which of these solutions would cause it to swell?

Answers

Answer:

The contents of a cell if has the solute concentration as 0.04 percent then it should have much lesser concentration that the cell, then only it will allow the cell to swell. Because of the solutions with a lower osmotic pressure than a cell fluid solution concentration, can make it swell.

Explanation:

Only a few thousand years
passed between the
appearance of life on Earth
and the appearance of
dinosaurs
True or false?

Answers

False more like millions

Answer:

hlw its jess bragoli

your answer is here

• false

Explanation:

The dinosaurs died out 65 million ago

and 65 million is a lot. Not a few

so your ans will be

false

Can you add nutrition please?

Answers

Answer:

yes we can add nutrition from healthy and nutritious foods .

hope it is helpful to you

Question 3 of 10
What is the next step in the scientific method, following stating a question?
A. Analyzing the data
B. Forming a hypothesis
C. Collecting the data

Answers

Answer:

B. Forming a hypothesis

Explanation:

Once you have a question in mind, you form a hypothesis (which is sort of an educated guess of what you expect or do not expect to happen) and then finally you can start on scientific investigations of collecting data and end with analyzing data and showing conclusion.

Answer:

the correct answer is B

Explanation:

because you always try to understand your question after you state it

This mountain slope towers over a town several hundred feet below. Which two weather events present the highest risk to the town

Answers

avalanche or rock slide

Describe the biome in which you currently live, or one in which you want to live, or have lived. What are the atmospheric conditions (wind pattern, humidity level, etc), solar intensity, and geographic/oceanographic features that have produced this unique ecosystem

Answers

Answer:

Southern Texas

Explanation:

The Wind pattern often is represented by the westerlies, which are the winds that flow in the northern latitude of the world. The humidity level in this zone varies from 10-20%, since we are in the desert we do not have much humidity, the solar intensity is high, often found in the 9-10 uv range, it is not advised to spend more than 10 minutes on direct sun without solar protection.  We have the Rio Grande to the south and some spare mountains.

Answer:

Southern Texas

Explanation:

High blood pressure may lead to strokes and heart attacks and is a risk factor that may be changed by taking medication?

Answers

Answer:

Yes

Explanation:

High blood pressure can be redused, but can't stop permanently.

yes it can be… wjdhsjdjsjsjjwjssjnxns

What is the
nature of water molecules makes that able to absorb heat and moderate our
climate.

Answers

the answer is hydrogen bonds i’m pretty sure. if not i’m sorry!!:)

The bacterium Salmonella enterica can cause severe food poisoning and the lining of the alimentary canal may be damaged. In these cases absorption of digested food products cannot easily take place. Which region of the alimentary canal is most affected?
A colon B ileum C oesophagus D stomach​

Answers

The duodenum is largely responsible for the continuing breakdown process, with the jejunum and ileum being mainly responsible for absorption of nutrients into the bloodstream. Subsequently the waste moves into the large intestine (large bowel or colon) for excretion through anus

Arrange the biological terms from smallest to largest.
Ecosystem
Population
Cell
Tissue
Biosphere
Molecule
Organism
Atom

Answers

Atom,molecule,cell,tissue,organism,population,ecosystem,biosphere.

Answer:

atom - molecule- Cell -tissue - organism- population- ecosystem-biosphere


2. What is the longest wavelength?

Answers

Answer:

red

Explanation:

Visible light may be a tiny part of the electromagnetic spectrum, but there are still many variations of wavelengths. We see these variations as colors. On one end of the spectrum is red light, with the longest wavelength. Blue or violet light has the shortest wavelength.

Answer:

red has the longest wavelength.

Explanation:

blue and violet are the shortest

Please please help!!

Answers

pick what u picked it’s best choice

Answer:

option 3

Explanation:

How many chromosomes do each sex cell have

Answers

[tex] \huge \tt{Hello...!}[/tex]

My Answer

In humans, cells other than human sex cells, are diploid and have 23 pairs of chromosomes. Human sex cells (egg and sperm cells) contain a single set of chromosomes and are known as haploid.

I Hope it's Helps ╮(^▽^)╭

#CarryOnLearning

economic importance of mosquito larva list five​

Answers

Explanation:

economic importance of mosquito larva are

Mosquito larvae grow by consuming microorganisms such as algae and microbes that decompose decaying plant material. Larval mosquitoes contribute to aquatic food chains by serving as food sources for many predators, including fish and birds.i hope it will help you

What are the measures of <1 and <2 Show your work or explain your answers.

Answers

Answer:

<1=105 <2=75

Explanation:

So 2 is 75 degrees because it's corrosponding with <6.

75+<1=180

-75       -75

<1=105

Two different enzymes catalyze the same reaction and both exhibit the same Vmax. When Enzyme A was run with a 40 uM substrate, the initial rate (Vo) was 10 uM/min, and when g it was run with a 4 mM substrate, the Vo was 20 uM/min. Estimate the approximate Vmax and Km of Enzyme A. When Enzyme B was run with 80 uM substrate, the initial rate (Vo) was 10 uM per minute. Estimate the Km of Enzyme B.

Answers

Answer:

a) k_m = 4.08 uM

  V_{max} = 20.07 uM/min

b) k_m = 8.16 uM

Explanation:

Given that:

For Enzyme A:

the substrate concentration [S] = 40 uM

the initial velocity rate v = 10 uM/min

when it was 4mM, v = 20 uM/min

i.e.

at 4mM = 4000 uM;

Using Michealis -menten equation;

when v = 10

[tex]V = \dfrac{V_{max}[S]}{k_m+[S]}[/tex]

[tex]10 = \dfrac{V_{max}\times 40}{k_m + 40}[/tex]

[tex]10 (k_m + 40) = V_{max}40[/tex]

[tex]40V_{max} -10k_m = 400 --- (1)[/tex]

when v= 20

[tex]20= \dfrac{V_{max}\times 4000}{k_m + 4000}[/tex]

[tex]20 (k_m + 4000) = V_{max}4000[/tex]

[tex]4000V_{max} -20k_m = 8000 --- (2)[/tex]

equating equation (1) and (2):

[tex]40V_{max} -10k_m = 400 --- (1)[/tex]

[tex]4000V_{max} -20k_m = 8000 --- (2)[/tex]

let multiply equation (1) by 100 and equation (2) by 1

4000V_{max} - 1000K_m = 4000

4000V_{max} - 20 k_m = 8000    

  0        -980k_m = 4000

k_m = 4000/-980

k_m = 4.08 uM

replacing the value of k_m into equation (1)

40{V_max } - 10(4.08) = 400

40{V_max } - 40.8 = 400

40{V_max } = 400 +  40.8

40{V_max } = 440.8

V_{max} = 440.8/40

V_{max} = 11.02 uM/min

b)

Since V_{max} of A ie equivalent to that of B; then:

V_{max} of B = 11.02 uM/min

Here;

[S] = 80  uM

V = 10 uM/min

[tex]10 = \dfrac{11.02 \times 80}{k_m + 80 }[/tex]

10(k_m +80) = 881.6

10k_m = 881.6  - 800

10k_m = 81.6

k_m = 81.6/10

k_m = 8.16 uM

The arctic fox has a diploid number of 50 an arctic fox was forming gametes by meiosis, how many chromosomes would be visible in prophase 17 Are the chromosomes replicated or non-replicated?
a. 2. 50; unreplicated
b. 28; replicated
c. 100, replicated
d. 25: unreplicated
e. 6.50; Replicated

Answers

Answer:

50 visible chromosomes and replicated.

Explanation:

Diploid number 50Haploid number 25

When we talk about the cell cycle, we refer to the interphase and the cell division (mitosis or meiosis).

Interphase is composed of stages G1, S, and G2. During the S stage, the DNI replication process occurs. This is the only stage in which the DNI molecule replicates. The synthesis of histones and other associated proteins also occurs.

Meiosis occurs after the interphase is over.

Meiosis produces four daughter haploid cells (n) from a diploid germ cell (2n). Each daughter cell is haploid because they have half the number of chromosomes of the original one.

At the beginning of prophase 1, DNI is condensed in a well-defined chromosome formed by two sister chromatids joined by a centromere. Each chromosome carefully pairs with its homologous chromosome. Homologous chromosomes aline together to make the crossing-over possible, the stage where they interchange their parts.

The whole set of chromosomes is present in prophase 1. The reduction occurs later.

So if the germ cell has 50 chromosomes, the same 50 will be visible during prophase 1. DNA has already been replicated during the S stage of interphase.

which definition best describes a buffer?

Answers

Answer:

where are the options

Explanation:

A buffer is a solution that resists changes in pH upon the addition of a small amount of strong acid or strong base. ... A buffer is composed of a mixture·of a weak acid its conjugate base. (Sometimes a solution that is technically a buffer does NOT resist changes in pH.

Explain why the definition of a quality life is highly individualized.

Answers

to put it briefly, its because no one likes to struggle. Everyone wants to live comfortable without a worry to the world. when they see someone who has accomplished that state of life, they envy, or admire that person deeply. when you see that new loui bag or gucci belt, you instantly have this desire to own luxury things.

functions of the female reproductive organs​

Answers

Are there certain ones you need, like ovaries, vagina, uterus

Birds differ from their closest relatives, the reptiles, in what ways?
(choose all that apply)
the bones of reptiles are too lightweight to permit flight
birds are capable of powered flight, while some reptiles can glide
birds have feathers, reptiles have scales
only the birds lay eggs on land; the reptiles can only lay their eggs in water
the reptiles have a series of internal air sacs that allow a very efficient extraction of oxygen
birds are endothermic, while reptiles are generally ectothermic
1 pts

Answers

Answer:

birds have feathers, reptiles have scales

birds are endothermic, while reptiles are generally ectothermic

Explanation:

The main difference between birds and reptiles  is that birds have feathers on their body while on the other hand, reptiles ahve dry skin and have scales. Reptiles are ectotherms, while birds are endotherms. An ectotherm relies on its external environment to regulate the temperature of its body whereas Endotherms are able to regulate their body temperatures by producing heat within the body.

which characteristic of water allows it to absorb large amounts of energy without a large rise in temperature

Answers

Answer:

Specific heat capacity

Explanation:

The number of organisms that an area of land can sustain over a long period time is known as

Answers

Answer:

Carrying Capacity

Explanation:

Question 11
Plasmids are located
in the nucleus
continuous with the nuclear envelope
in the cytoplasm
in the nucleolus

Answers

Answer: eurkayotic cells

Explanation:

The oxidase test is another biochemical test used to distinguish aerobic versus anaerobic metabolism in microbes. Research the oxidase test and describe how it is performed. Include examples of oxidase-positive and oxidase-negative microbes in your answer.

Answers

The Bacillus genus is usually negative in regards for the Oxidase test.

Oxidase test is a biochemical test that is used to identify organisms that produce the enzyme  oxidase.

Oxidase test is used to distinguish aerobic from anaerobic metabolism in microbes.

Aerobic metabolism is the use of oxygen to generate energy from a food source while anaerobic metabolism is the generation of energy with the absence of oxygen.

The procedure of oxidase test includes:

Place a piece of filter paper in a clean petri dish and add 2 or 3 drops of freshly prepared oxidase reagent.Using a piece of stick or glass rod (not anoxidized wire loop), remove a colony of the test organism and smear it on the filter paper.Look for the development of a blue-purplecolour within a few seconds as shown in colour

Blue purple colour signifies oxidase positive organisms which includes Pseudomonas aeruginosa

Colourless signifies oxidase negative organisms which includes Escherichia coli

Learn more here:

https://brainly.com/question/4680704

•. What is the phenotypic ratio of complementary gene?
a) 1:2:1
b) 9:7
c) 13:3
d) 9:3:3:1​

Answers

I think the answer is b

How does carbon dioxide travel in blood via dissolved form

Answers

Answer:

carbon dioxide is more soluble in water than oxygen and hence is mostly transported in the dissolved form in our blood.

Carbon dioxide can be transported through the blood via three methods. It is dissolved directly in the blood, bound to plasma proteins or hemoglobin, or converted into bicarbonate.

The majority of carbon dioxide is transported as part of the bicarbonate system.

Goodluck

__________ law, which helps explain the critical closing pressure, states that the force that stretches the vascular wall is proportional to the diameter of the vessel times the blood pressure.

Answers

Answer:

Laplace law

Explanation:

Have a nice day :)

What is the 'processor of thermoregulation that determines if a change in
body temperature is needed?
A. Thyroid
B. Pancreas
C. Kidneys
D. Hypothalamus

Answers

Answer:

D) Hypothalamus

Explanation:

Other Questions
Find an equation for a line with slope of 3/4 passing through (2, -3) HELP ME PLSSSSSSif f(x) = 2x-3/5 , which of the following is the inverse of f(x)? Help NOW RIGHT NOW Enlist any four components of operating environment. Aidez moi I will make you brainliest Saved In order to be used as a primary key, which of these characteristics must an attribute possess with respect to a single instance of the entity? Select all that apply. There must be a maximum of one attribute instance. There must be many instances of the attribute There must be at most one entity instance that each attribute instance describes. There must be at least one instance of the attribute. There must be zero or more instances of the attribute. Question 2 (2 points) True or false: A singular attribute is also known as a unique attribute. True False Question 3 (3 points) Saved Relationship names and types of relationship maxima or minima that each could have are listed below. Match each relationship in the list below to the type of relationship maxima or minima. Instructions: Choose your responses from the drop-down menus below. Response options cannot be used more than once. Minima is One-Zero 1 Person-Assigned Social SecurityNumber 4 Minima is Zero Zero 2 CubicleNumber-Assigned-to- Employee per shift 2 Maxima is One-Many 3. Birthdate-Recorded-for-a Person 1 Maxima is One One 4. Women-Bearing-Children Question 4 (2 points) Saved A ride-sharing app's discount system for riders is configured such that a ride discount is triggered only if at least two RiderlDs book a ride in the same Card at the same time. Which of the following is true of the relationship Ride Discount-is-Applicable? The relationship minimum is Many-One. The relationship minimum is Two-One. The relationship maximum is One-Two. The relationship minimum is One-Two. 32 1/3% of animals at an animal shelter are dogs. About what fraction of the animals are dogs What is the y-intercept of this quadratic function? f(x)= -x^2 6. Who is likely to disagree with Nash's viewpoint? Why? Please help Body composition refers to Evaluate each of the following expression giving the answer in scientific notation Hi guy can you help me to make a introductory paragraph about smartphone. Please I need only introductory. A constellations changing position in the sky, at the same time of the evening, over a period of several weeks is evidence that:a- Earth is round b- Earths axis is tilted. c- Earth rotates on its axis.d- Earth revolves around the sun. WILL GIVE BRAINLIEST 15 POINTSDetermine how the triangles can be proven similar.AA~SSS~SAS~Not similar Tom had some blocks that were all the same size and shape. He used two of them to make this regular hexagon He placed six more blocks around this hexagon to make a bigger regular hexagon How many more blocks does he need to place around this shape to make the next bigger regular hexagon? (A) 6(B) 10 (C) 12 (D) 18 1a. If an escape room partyhas 16 participants and 4escape puzzles: How many staff areneeded? Write an expression tosolve how many staffare needed. 23. From the perspective of many Arab Muslims at the time of theCrusades, the European Crusaders were considered*A. refugeesB. invadersC. liberators. D. allies Consider the following functions. f(x) = x2, g(x) = x + 9 Find (f g)(x). Find the domain of (f g)(x). (Enter your answer using interval notation.) Find (g f)(x). Find the domain of (g f)(x). (Enter your answer using interval notation.) Find (f f)(x). Find the domain of (f f)(x). (Enter your answer using interval notation.) Find (g g)(x). Find the domain of (g g)(x). (Enter your answer using interval notat How would the author of passage 2 most effectively respond to the ideas in the last sentence?