how enzymes inhibitions studies in the formulation and development of drugs​

Answers

Answer 1

Answer:

Enzyme inhibitors may alter the elimination rate of a particular drug or inhibit detoxication pathways

Explanation:

An enzyme inhibitor is a chemical compound capable of binding to an enzyme in order to reduce its activity. An enzyme inhibitor may bind to an active site and thus decreases the rate of reaction (direct inhibition). Enzyme inhibitors may act 1-to Inhibit detoxification enzymes and 2-reduce the elimination rate of enzyme drugs, thereby having dose-dependent toxicity effects. For example, many medicines are based on the inhibition of Cytochromes P450 (CYPs) proteins, which are a superfamily of enzymes required for drug metabolism.


Related Questions

Based on the information provided in the map, propose a way cholera may be transmitted.

Answers

Answer:

5

Explanation:

g

The six modes of disease transmission shown in the Model 2 are

1. Airborne

What is airborne?

The Airborne transmission can be caused by coughing, sneezing where

water droplets carry the disease causing organisms.

Example: flu, tuberculosis, etc.,

2. Food borne or waterborne

The pathogen is transmitted by the consumption of contaminated

food or water

Eg: cholera, botunilsm, etc.,

3. Vector

The vector such as insects or animals can act as vectors by carrying disease causing malaria, dengue.

4. Blood borne

The disease is caused by the transmission of blood or contact of

injured cuts or incisions.

Example: hepatitis, AIDS, etc

5. Contact

The disease is caused by the person to person direct contact of skin to skin such as leprosy, skin and eye infections, fungal infections, etc.,

6. Seˣual

The disease is seˣually transmitted are AIDS, gonorrhea, syphilis.

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Adjustments to timber management strategies meant to address long-term shortfalls will _______.
a.
result in immediate increases in available supplies
b.
lead to initial shortfalls in timber supplies
c.
initially decrease the cost of timber
d.
ultimately result in more expensive timber

Answers

Answer:B lead to initial shortfalls In Timber supplies

Explanation: I got it right

Answer:

B

Explanation:

ILL GIVE YOU BRAINLIEST HELP ASAP!

Even the most successful entrepreneurs are unable to add to economic growth locally, nationally, or even globally.

A.
True

B.
False

Answers

Answer:

I think True

Explanation:

Hope this helps

The answer would be True
Hope this helps!

The table below shows the two surface features and the processes that are likely to form them.


Surface Features and Processes

Feature Process

Coastline A

Sea Cliff B


Which processes are represented by A and B?

Group of answer choices


A = erosion by wind and water; B = erosion by water


A = erosion by water; B = deposition and erosion by wind


A = deposition; B = deposition


A = erosion by wind; B = erosion by wind

Answers

Answer:

B

Explanation:

trust meeeeeeeeeeeeeeeeeeeeeeeeeeeeeee

Type the correct answer in the box. Spell all words correctly.
What is the correct term for a large number of species in an ecosystem?
An ecosystem with a large number of species is said to have__________

Answers

A large number of species in an ecosystem can be collectively termed as biodiversity.

All of the following climate regions are labeled on the map above except
A humid subtropical
B. tropical wet
C. highland
D. arid
Please select the best answer from the choices provided
A
B

Answers

I if it’s eastern geo I think it’s D if I get it wrong I’m sorry

Answer:

The answer is c

Explanation:

What is one function of the organ system shown below in the picture?

Answers

The main function of the lungs is the process of gas exchange called respiration (or breathing). In respiration, oxygen from incoming air enters the blood, and carbon dioxide, a waste gas from the metabolism, leaves the blood. A reduced lung function means that the ability of lungs to exchange gases is reduced.

The circulatory and respiratory systems are involved in respiration. They provide oxygen to the body cells and remove carbon dioxyde. The correct option is A. To remove carbon dioxyde from the body.

Two systems work together when providing oxygen to the body cells and removing carbon dioxide: The circulatory and respiratory systems

• Respiratory system

This system is in charge of the gasses interchange. It takes oxygen from the air and releases carbon dioxide.

• Circulatory system

This system is in charge of driving oxygen to the organism's tissues and cells and taking away carbon dioxide from them.

These gases are in the oxygenated and deoxygenated blood, respectively.

The heart bombs blood through arteries, veins, and capillaries to the whole body.

The blood carries oxygen to different tissues.

This oxygen is absorbed in the lungs and proceeds from the air that we breathe. Its final destiny is all the cells in the organisms.

Types of circulation

• Lung circulation

1. Moves blood between the heart and the lungs.

2. Deoxygenated blood goes from the heart to the lungs

3. In the lungs, deoxygenated blood releases carbon dioxide and gets oxygenated again.

4. Carbon dioxide is released by exhalation.

5. Blood absorbs oxygen from small air sacs named alveoli.

6. Oxygenated blood returns to the heart.

Systemic circulation

1. Carries blood between the heart and the rest of the body.

2. Oxygenated blood leaves the heart and moves to all the cells in the body.

3. Deoxygenated blood returns from tissues to the heart.

According to thi framework, the function of the organ system shown in the picture is to remove carbon dioxyde from the body. Option A.

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Someone plzzz help with this question

Answers

Answer:

Ion

Explanation:

An Ion is exactly as stated it bears either a positive or negative charge.

Role of Ibn Sina in the field of medicine?

Answers

Answer:

Although Avicenna made advances in pharmacology and in clinical practice, his greatest contribution was probably in the philosophy of medicine. He created a system of medicine that today we would call “holistic” and in which physical and psychological factors, drugs, and diet were combined in treating patients.

Explanation:

I hope I helped

Answer:

Although Avicenna made advances in pharmacology and in clinical practice, his greatest contribution was probably in the philosophy of medicine. He created a system of medicine that today we would call “holistic” and in which physical and psychological factors, drugs, and diet were combined in treating patients.

Explanation:

Hope it helped

Mark me Brilliant

5 Stars

5 Hearts

can you help me with this
Thank you​

Answers

Answer:

option c is correct friend...

C is the answer duuddee

Over time, a tree that once had a total mass of
300 g increased in mass to 3000 kg. This increase
in mass comes mostly from
(1) carbon dioxide that enters through the leaf
openings
(2) oxygen that enters through the leaf openings
(3) soil that all plants need to grow
(4) chloroplasts that enter the roots and move to
the leaves

WHAT IS ITTTT

Answers

Answer:

carbon dioxide that enters through the leaf

openings

Explanation:

Drag the steps into the correct order to show how plants use energy from the sun. Start with the first step on top.


The sun shines on a plant.


The plant makes sugar and oxygen.


Chlorophyll traps energy from the sun.


Cells use sugar for energy.
PLEASE ANSWER QUICK! WILL GIVE 5 STARS AND A THANKS IF CORRECT. mAYBE BRAINLIEST AS WELL

Answers

Answer:

1. The sun shines on a plant 2.chlorophyll traps energy from the sun 3. the plant makes sugar and oxygen 4.cells use sugar for energy

Explanation:

this might be

what did scientists learn about the common garden study?

Answers

Answer:

The results of this study suggest that discordance in divergence between morphological characters and molecular genetic markers may represent an opportunity to understand ecological mechanisms of incipient specialization.

Explanation:

Choose the CORRECT statement about enzymes below.
Group of answer choices

Enzymes raise the activation energy needed in a chemical reaction

Enzymes slow down the rate of chemical reactions

Enzymes function best at specific pH and temperatures

Enzymes are carbohydrates and store short term energy

Answers

Answer:

Enzymes function best at specific pH and temperatures.

Explanation:

An enzyme can be defined as a biological catalyst that typically lowers the activation energy of a biological reaction. When the activation energy of a reaction is low, the rate of the reaction would be faster. Therefore, an enzyme speeds or catalyzes the rate of a reaction by lowering its activation energy.

Also, if the conditions are not optimal for an enzyme, it limits the ability of an enzyme to bind or be joined with its substrates.

Hence, the correct statement about enzymes is that enzymes function best at specific pH and temperatures. An increase in temperature increases or speeds up the rate of a reaction while low temperature limits or reduces the rate of a reaction. The optimal temperature for enzymes in the human body is around 37 degrees celsius.

Which amino acid will be carried to a ribosome by a transfer molecule contining the anticodon AAA?

Answers

TTT? I am not entirely sure, as you would have to know all of the amino acid codes. Sorry I can’t help more:(

why RNA is always single stranded and DNA is double stranded

Answers

Answer:

The DNA is very stable in it's double helix form. RNAs are relatively unstable and easy to degrade because they are single stranded. They are single- stranded so that translational proteins may read then and produce proteins.

Explanation:

Hoped this helped!

Brainly, please?

The DNA is very stable in it's double helix form. RNAs are relatively unstable and easy to degrade because they are single stranded. They are single stranded so that translational proteins may read then and produce proteins.

Pls help me on this question this is on IXL

Answers

Answer:

Twice

Explanation:

If four cells went through mitosis at the same time how many daughter cells would be formed?

Answers

Explanation:

4 it like he ii http HDD bee bee bee

Can someone please help me

Answers

Answer:

letter D

Explanation:

LETTER D•Enzymes Are usually Carbohydrates


HELPPP
A vertebrate depends on a variety of body systems, including the nervous, respiratory, digestive, circulatory,
skeletal, and muscular systems. Which statement BEST describes the relationships among the systems?
A )Each system works independently, but may sometimes complete tasks that generally are performed
by another system
B)Each system works independently and depends only minimally on other systems.
C )Each system typically works together with other systems, but sometimes functions independently.
D) Each system works closely with other systems, and could never function independently.

Answers

Answer:

D a system could never work independently they all are dependent on each other to peform its given function

A couple comes to a genetic councilor concerned about their chances of having a baby with Tay Sachs disease. The husband had a sibling die of the disease, which is inherited as a autosomal recessive trait. What are the chances that he is a carrier?

Answers

Answer:

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Explanation:

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HELP 25 POINTS AND BRIANLIEST IF CORRECT

Thoroughbreds are an example of a type of horse that results from selective breeding. However, not all thoroughbreds have the traits that are most desired. How has the process of selective breeding increased the probability that the horse will have a desired trait? Use information from the stimulus material and your knowledge of science in your answer. In your answer, be sure to:

Explain how selective breeding increases the probability that offspring will have a desired trait.
Explain why not all individual thoroughbreds may express the desired traits.

Answers

Answer:

If breeders Breed these horses with other breeds, the foal wont be a straight thoroughbred. So, it will change the horses breed.

Explanation:

Selective breeding increases the probability that offspring will have the desired trait because it limits narrows the gene pool to only include desired variants of a gene. Not all thoroughbreds may express the desired trait because they may inherit an unwanted variant of the gene & mutations may occur.

The traits and characteristics of an animal are determined by the genes they possess. When two animals breed, the offspring inherits one variant of each gene from both parents, known as alleles. This means that all animals have 2 variants for any specific trait.

When a gene in an allele is expressed, it means that the genetic code in that allele is the one that can be seen on the offspring. Gene variants can be classified based on how likely they are to be expressed as:

Dominant Recessive

When one allele is expressed and the other is not, it is because that allele is dominant and the other is recessive. Recessive variants for a gene will only be expressed if both alleles inherited by the offspring possess are recessive. dominant genes are symbolized by a capital letter and recessive genes with a lower-case letter.

Selective breeding is used to continuously breed animals that have similar variants of the desired trait. If breeding were to be natural, then many of what we consider desirable traits may be lost behind the expression of common, more dominant genes. Selective breeding is done by narrowing the gene pool, meaning that we only allow breeding between animals known to possess the desired trait.

Not all thoroughbreds may express the desired traits because sometimes even though a parent has the desired variant of a trait, they may also contain a different recessive or dominant variant of a trait. Since selective breeding does not control what variant exactly the offspring inherits, it does not always work with each offspring. Genetic mutations can also affect the outcome.

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Hypersecretion of growth hormone after normal growth has ceased may cause

acromegaly

achondroplastic dwarfism

pituitary dwarfism

gigantism

Answers

Answer:

gigantism

Explanation:

The growth hormone is responsible for stimulating normal growth in humans or in other words, stimulating growth at a normal pace. To do this, the growth hormone must be released in optimal quantities, however, an hypersecretion i.e. excessive release of the hormone will cause a fast and uncontrollable growth in certain regions of their body or the whole.

This abnormal excessive growth caused by an excessive release of the growth hormone is called GIGANTISM. Gigantism occurs mostly in children at their growing phase.

l. A farming area developed a major locust problem. Swarms of locusts were destroying crops and the environment. A team of
scientists developed an infectious disease that would reduce the population of locusts What would be most important to find
out before producing and releasing the disease?
how a decreased number of locusts would affect other organisms
which species might eat the crops in the absence of locusts
how the disease can be used for other applications
O how quickly farmers would get to see the results

Answers

Answer: how a decreased number of locusts would affect other organisms.

Explanation:

When engaging in any action aimed at destroying large numbers of an organism as is the case here, there is always a need to check what impact it might have on the ecosystem at large.

This is why it is very important that the effect of a decreased number of locusts on other organisms is evaluated before such drastic action is taken. If it would lead to a situation where the ecosystem is destabilized, the consequences would be far reaching and very damaging.

How a decreased number of locusts would affect other organisms is the

most important to find out before producing the disease.

What is Population?

This is referred to the number of organisms present in an area over a

specific period of time.

We were told that swarms of locusts destroyed the environment and

needed to be reduced through the creation of a disease. The effect the  

decrease in locust  has on other organisms has to be considered to ensure

the ecosystem is balanced and doesn't adversely affect others.

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Which of the following statements about human society and limiting factors is true?
a. Modifications made to the environment to reduce the impact of limiting factors can cause
disruption to the natural balance of an ecosystem.
b. Humans cannot modify their environment to adapt it to their needs.
c. Humans can completely overcome the factors that limit population size.
d. Limiting factors are of no concern to human society, because they do not affect human
populations

Answers

The statement that is true about human society and limiting factors is "Modifications made to the environment to reduce the impact of limiting factors can cause disruption to the natural balance of an ecosystem." The correct option is A.

What are limiting factors?

Limiting factors are the factors that limit the growth of populations. For instance, the limiting factors for humans might be a lack of food or water. Limiting factors may be biotic or abiotic. Abiotic factors include nonliving aspects like temperature and rainfall while biotic factors are the living aspects like predators and competition.

Modifications made to the environment to reduce the impact of limiting factors can cause disruption to the natural balance of an ecosystem. These modifications include the introduction of a new species, the clearing of land for agriculture or industry, or pollution.

The new species can lead to the elimination of the native species, the clearing of land can cause habitat loss, and pollution can have numerous effects like air and water pollution.

Therefore, the correct option is A.

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Which three events that affect Earth's crust happen very quickly?
A. Earthquakes
B. Folding
C. Fault formation
D. Volcanic eruptions

Answers

Answer:

Earthquakes,volcanic eruptions and i think fault formation sorry if this is incorrect but i'm pretty sure this is correct.

Explanation:

list 5 disorders that affect male reproductive system and discuss them​

Answers

Answer:

Prostate CancerTesticular CancerMale infertility Testosterone Deficiency Enlarged prostate or BPH

Match the correct action to what is happening in the cell.
1. Break open the cell
2. Dissolve the membranes 3. Separate the organelles, broken cell walls, and membranes from proteins, carbohydrates and DNA
4. Precipitate the DNA(clump the DNA together)

A. Squish the fruit to a slush
B. Filter your extract through cheesecloth
C. Layer cold alcohol over the extract
D. Mix in a detergent(soap) solution

Answers

Answer:

i have no idea you need to give me more info

Explanation:

PLEASE HELP!!!!

Which 2 lines in the graph below DO NOT shows a population in equilibrium as described by the Hardy-Weinberg principle?

Answers

The correct answer is Population A and C

In mice black fur is dominant to white fur. Neither parent of these have the recessive phenotype. what genotypes are the parent mice?

Answers

black: B (dominant allele)
white: b (recessive allele)

If no one has the recessive allele (lowercase), then they must have BB.

Genotype is the genetic makeup of an organism; phenotype is the physical representation

I hope this helps!
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