Cystic fibrosis is an autosomal recessive disorder where a chloride ion membrane channel protein doesn't function properly. People with cystic fibrosis suffer from chronic lung infections that make breathing very difficult. They also suffer from other issues such as an inability to produce enough digestive enzymes due to problems with pancreas cells. Suppose that Chris and Shannon are both carrier of cystic fibrosis (carriers have the allele but do not exhibit the disorder). What is Chris' genotype for the cystic fibrosis gene

Answers

Answer 1

Answer: Typically, the genotype in those patients consists of at least one very mild mutation uncharacteristic for CF patients. These are predominantly missense or splice variants, belonging to classes IV or V producing variable amounts of functional CFTR protein at the apical membrane.


Related Questions

why is it important to determine the manner/mechanism of death

Answers

no i decide when someone death is coming. and i’m always right like i can say your death is tomorrow and u will pass away tmr !!

A pair of identical twins develop leukemias, where immature white blood cells proliferate uncontrollably. In each case, the cancer cells analyzed from identical twins displayed an identical chromosomal mutation and this critical mutation was not found in the twins normal cells. The twins developed leukemia at different times in their lives. What is the best explanation for the origin of this chromosomal mutation

Answers

Answer:

The chromosomal rearrangement resulted from a rare somatic mutational event that occurred in utero

Explanation:

Leukemia is a progressive type of cancer where immature white blood cells (leukocytes) proliferate uncontrollably. Next-generation sequencing (NGS) technologies have shown that somatic mutations are relatively common in different types of leukemia such as, for example, acute myeloid leukemia (AML). Moreover, identical twins are developed from one fertilized egg (ovum) that splits and develops into two identical individuals that share all of their genes (i.e., they have exactly the same genetic information). In this case, it is expected that leukemogenesis was initiated in the utero by the occurrence of a chromosomal rearrangement and proceeded early during development as distinct clonalities. In addition, the fact that identical twins developed leukemia at different times in their lives also indicates that this malignancy wasn't caused by only one mutation, but instead it was triggered by multiple mutational events (i.e., leukemia is a multistep cancer caused by secondary genetic changes).

Where would you collect
data during an
experiment?

Answers

Answer:

Recall that data can be collected in two main ways: (1) through sample surveys or (2) through designed experiments. While sample surveys lead to observational studies, designed experiments enable researchers to control variables, leading to additional conclusions.

The fossil presence of anatomically modern humans in ________ demonstrates that our ancestors were capable of substantial water crossings by 40,000 years ago.

Answers

Answer:

The correct answer is - Africa.

Explanation:

Scientists found the fossils of modern humans called Mota an ancient man who lived around 40000 to 45000 years ago in Ethiopia. It was the first DNA isolated from Africa.

This DNA sample says that the Europeans have 6% of the DNA of this modern human, which suggests that there was substantial migration of people into Africa from Europe and the middle east by water crossings.

Is bacteria prokaryotic or eukaryotic

Answers

The answer to this question is Prokaryotes
It’s the second word

The relationship between the remora and the shark is an example of - (5.5)

A predation
B commensalism
C parasitism
D mutualism

Answers

D.mutualism,both parties benefit
the relationship is commensalism because the remora attaches onto the sharks underbelly and whatever the shark eats, the extra fallen pieces end up to the remora

Definition of respiration​

Answers

a process in living organisms involving the production of energy, typically with the intake of oxygen and the release of carbon dioxide from the oxidation of complex organic substances

Answer:

A process of oracajsjsjsjsjsjjss

Explanation:

Nithingbs lol just for poimts

Need help again ASAP

What does the data reveal about the relationship(s) between the impactor's mass and crater depth?

Answers

Answer:

For each ball, the crater diameter increased as the height of the ball drop increased. My conclusion is that crater diameter increases with increasing mass. Also as the height of the ball increases, so does the crater diameter. Thus crater diameter is proportional to the mass and velocity of the impactor.

Explanation:

correct me if im wrong!:-)

Auxins cause cells to grow ___. A. Longer on the sunny side of the stem. B. Shorter on the sunny side of the stem . C.shorter on the shaded side of the stem .d. Longer on the shades side of the stem

Answers

Answer:

D. Longer on the shaded side of the stem

Explanation:

Auxin is a plant hormone that promotes cell growth and elongation in plant stems.

It causes the cells to grow longer on the shaded side of the stem.

This growth allows for the plant to grow in the direction of the light source it has.

So, the correct answer is D. Longer on the shaded side of the stem

HELP WITH THESE ASAP NO LINKS PLS

Answers

16. should be B) Chemical Properties of Water.

Because those are all examples of chemical changes of water.

17. should be B) The liquid will remain a liquid.

Because 52° C is the same as 125.6° F.

Please match the following terms with the appropriate definitions.
Distance

[ Choose ]
Displacement

[ Choose ]
Slope

[ Choose ]
SI unit for speed and velocity

[ Choose ]
SI unit for acceleration

[ Choose ]

Answers

Distance - an amount of space between two things

Displacement - something that is moved from original place or the area between a object when place in water (volume)

Slope - rise over run or an angle of a line

Sl unit for speed and velocity - meter per second

Sl unit for acceleration - meter per second squared

Which of the following are the products of respiration?
1)ATP, Water, and Oxygen
2)Carbon dioxide, Oxygen, and Water
3)ATP, Carbon Dioxide, and Water
4)Glucose, Water, and Carbon Dioxide

Answers

3 would be the best choice of cellular respiration

PLS HELP!! ASAP DUE TONIGHT!!

The saturated fats of animals differ from the unsaturated ones of plants. Unsaturated fats have

A. higher molecular weights.

B. more metabolic processes that they participate in.

C. nitrogen atoms in their structures.

D. a higher number of double bonds between carbon atoms in their structures.

E. more functional utility in animal species, particularly in marine life forms.

Answers

Answer:

D. a higher number of double bonds between carbon atoms in their structures.

Explanation:

Non vascular plants are quite commin in the forests along the coast of Norther California but are relatively rare in the ecosystems around Davis in the Central Valley. What aspects of the life cycle of these plants make it difficult for them to reproduce on our area

Answers

Answer:

The Central Valley of northern California is a region where there is little water supply, while nonvascular plants cannot efficiently store water and they have primitive traits that are dependent on water for reproduction.

Explanation:

The Central Valley of northern California is characterized to have little natural precipitation/snowmelt during the dry summer months. In addition, California's climate also has extended periods of drought. On the other hand, non-vascular plants such as mosses and liverworts, are a type of plant that lacks vascular tissues (xylem and phloem), and they also lack true roots, stems, or leaves. These plants cannot efficiently absorb and store water (which fundamental for survival), and thereby the success of these plants in establishing and reproducing in the ecosystems of the Central Valley is limited to their physiological tolerance to desiccation. Moreover, non-vascular plants may also exhibit primitive traits related to their reproductive cycle (e.g., a flagellated sperm) that are dependent on water for reproduction.

True or False? The skills and characteristics needed for a high-quality friendship are the same skills and characteristics needed in a committed long-term relationship or marriage.

Answers

True
Hope this help

How much time does it take to use 300 W of power to do 1800 J of work? Round your answer to the near
number.
SERE
The time is
S.

Answers

Answer:

the answer is 6 secs rounded to nearest ten is 10

Explanation:

hope it helps

Purple flowers are a dominant trait while white flowers are a recessive trait.
Explain what this difference means in terms of the alleles for flower colour.

Answers

Answer:

the dominant trait will always over role

You put a cat in an open cage with cat food, water, and a litter box (where the cat poops and urinates). The cage cat water food litter box weighs 2000 grams. Two weeks later, the cat has eaten all the food, has drunk all the water, and has grown a little bit bigger. The cat's waste (urine and poop) is still in the litter box. How much would you expect the cage cat litter box with poop and urine to weigh now

Answers

Answer:

it would weigh more than before

Explanation:

1, name the part of the reproductive system in which fertilisation happens.
2, what is an embryo
3, where does the embryo develop into a foetus, and then a baby
4, why does the uterus lining start to grow thick and spongy, as an egg cell develops in an ovary
5, what happens to the uterus lining if the egg cell is not fertilised
6, how often does an egg cell leave an ovary, in an adult woman
7, how often does menstruation happen, in an adult woman

Answers

I’m going for real I haven’t done this because it was hard didn’t get it but now I know // ANSWER -

Answer:

°•°

Explanation:

1.fallopian tube

2.an unborn or unhatched offspring in the process of development, in particular a human offspring during the period from approximately the second to the eighth week after fertilization (after which it is usually termed a fetus)

3.First, the zygote becomes a solid ball of cells. Then it becomes a hollow ball of cells called a blastocyst. Inside the uterus, the blastocyst implants in the wall of the uterus, where it develops into an embryo attached to a placenta and surrounded by fluid-filled membranes.

4.Eggs live in ovaries, and the hormones that control your menstrual cycle cause a few eggs to mature every month. When your egg is mature, it means it's ready to be fertilized by a sperm cell. These hormones also make the lining of your uterus thick and spongy, which gets your body ready for pregnancy.

5.The fertilized egg attaches to the lining of the uterus. The placenta then develops. The placenta transfers nutrition and oxygen to the fetus from mother. If the egg does not become fertilized, the lining of the uterus (endometrium) is shed during menstruation.

6.The egg cell travels down the fallopian tube into the uterus. The moment the egg cell leaves the ovary is called ovulation. Once a girl has had her first monthly period, ovulation usually occurs once a month

7.The average menstrual cycle is 28 days long. Cycles can range anywhere from 21 to 35 days in adults and from 21 to 45 days in young teens. The rise and fall of levels of hormones during the month control the menstrual cycle.

2. How does temperature change in the troposphere?
A. It increases with height.
B. It decreases with height.
C. It increases and then decreases with height.

Answers

Answer:

OPTION-A IS CORRECT

IT INCREASES WITH HEIGHT

Explanation:

PLEASE MARK ME BRAINLIEST

Which of the following is not a kingdom of
life?

Answers

Hey, just a heads up there’s no picture ^*

Question is not complete....

Drag a number and symbol to represent the amount of time Carl worked on problems.

___ ___ ____


Answers

Answer:

25 - m

Explanation:

If Carl worked m less than 25, 25 - m would represent the amount of time Davis worked minus the difference in the amount of time that he and Carl worked, which would equal the amount of time Carl worked.

Is a fish a living organism?????????????????????????

Answers

Answer:

yes a fish is a living organism

Answer:

yes

Explanation:

it can move, eat and produce

How do increases in human consumption of natural
resources impact the Earth

Answers

Answer:

The impact of so many humans on the environment takes two major forms: consumption of resources such as land, food, water, air, fossil fuels and minerals. waste products as a result of consumption such as air and water pollutants, toxic materials and greenhouse gases.

hope it helps

cuál es el límite entre la cavidad torácica y abdominal?

Answers

Answer:

El diafragma es un músculo en forma de cúpula que separa la cavidad torácica (pulmones y corazón) de la cavidad abdominal (intestinos, estómago, hígado, etc.).

Explanation:

From this diagram of fossils (sorry it’s a bit blurry) which layer is the youngest and which layer is the oldest? How do you know?

Answers

Answer:

The bottom layer is the oldest, and the top layer is the youngest

Explanation:

As time goes on more and more sediment gets piled onto a certain place, meaning the oldest fossils will keep getting deeper and deeper

On a distance-time graph, a car standing still is shown with ____.

A. line curving down
B. line curving up
C. straight, horizontal line
D. series of dots getting closer together​

(science)

Answers

C

because time is still going by when the car isn’t moving

Answer:

yess i think it is c as well

Explanation:

hope you have a great day

To start an action potential moving down the axon, what must happen?​

Answers

Answer:

Different ions cross the neuron membrane and stimulus causes sodium channels to open I think.

what are all the zodiac names
if I was born in september what is my zodiac
I WILL GIVE 20 POINTS FOR THIS

Answers

Answer:

Virgo

Explanation:

Have a great day :)

Answer:

libra, cancer, aries, scorpio, leo, pisces, saggitarius, aqurious, capicorn, tarous, and gemini

Explanation:

Virgo

The zodiac sign for September  is Virgo.

This zodiac symbol is considered to influence those born August 23 - September 22, under the Virgo zodiac sign

pleaaaseeee helpp meeeeeee ​

Answers

4 is a pterodactyl!!!!!!
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